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Biology and Genetics -
Global Re-Emergence of Tuberculosis

Tuberculosis (TB) has re-emerged in recent decades with increased virulence in its original form and in a multidrug-resistant (MDR) tuberculosis form. The extensively drug-resistant (XDR) tuberculosis strain is resistant to all known tuberculosis treatment drugs, raising serious global public health concerns for its management.

There has been a notable increase in the number of TB patients globally.  The increase in the degree of drug resistance may be related in part to misuse and non-adherence to treatment regimes.  The re-emergence of tuberculosis has mainly affected those who are biologically vulnerable, due to immunodeficiency or HIV/AIDS, as well as those who are socioeconomically disadvantaged, and those living in overpopulated, enclosed spaces.  There are a number of interventions for the prevention, detection and treatment of TB that may help to mitigate the risk of contracting TB. National and international health authorities can use these strategies to combat the resurgence of TB in the interests of protecting public health. 


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Contributor:  Vanessa Do Couto

Last Reviewed:  October 17, 2014



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